Misrecognition and Critical Consciousness — An 18-Month-Old Boy with Pneumonia and Chronic Malnutrition

By Héctor Carrasco, M.D., M.P.H., Luke Messac, M.D., Ph.D., and Seth M. Holmes, M.D., Ph.D.

The New England Journal of Medicine June 20, 2019


An 18-month-old boy in La Soledad, Mexico, presents with pneumonia, to which he was predisposed by malnutrition. When nutrition education and food-production efforts fail, a physician and a community collaborative work to elucidate the deeper roots of the problem.

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Effect of High-Dose Vitamin D Supplementation on Upper Respiratory Tract Infection Symptom Severity in Healthy Children

By Katrina Hueniken, Mary Aglipay, Catherine S. Birken, Patricia C. Parkin, Mark B. Loeb, Kevin E.Thorpe, David W.H. Dai, Andreas Laupacis, Muhammad Mamdani, Tony Mazzulli, Jonathon L. Maguire on behalf of the TARGet Kids! Collaboration

The Pediatric Infectious Disease Journal, June 2019


Observational studies support the role of vitamin D in reducing viral upper respiratory tract infection (URTI) symptom severity in adults and children. This study assessed whether wintertime high-dose vitamin D supplementation (2000 IU/day) reduces URTI symptom severity compared with standard-dose (400 IU/day) supplementation in preschool children. Secondary objectives were to assess effects of high-dose supplementation on outpatient physician visits, emergency department (ED) visits and antibiotic prescriptions for URTI.

This was a secondary analysis of a multisite randomized clinical trial involving 703 healthy 1- to 5-year-old children in Toronto, Canada. High-dose or standard-dose oral vitamin D was randomly assigned for 1 winter season. For each URTI, parents completed symptom checklists based on the Canadian Acute Respiratory and Flu Scale. Symptom severity, frequency of outpatient visits, ED visits and antibiotic prescriptions for URTI between groups were analyzed using negative binomial regression.

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Day clinic versus hospital care of pneumonia and severe malnutrition in children under five: a randomized trial

By Hasan Ashraf  Nur H. Alam  Marufa Sultana  Selina A. Jahan  Nurshad Begum  Sharmin Farzana  Mohammod J. Chisti  Mohiuddin Kamal, et al.


Tropical Medicine & International Health, May 2, 2019


Randomized clinical trial where children aged 2 months to 5 years with pneumonia and severe malnutrition were randomly allocated to DC or inpatient hospital care. We used block randomization of variable length from 8-20 and produced computer-generated random numbers that were assigned to one of the two interventions. Successful management was defined as resolution of clinical signs of pneumonia and being discharged from the model of care (DC or hospital) without need for referral to a hospital (DC), or referral to another hospital. All the children in both DC and hospital received intramuscular ceftriaxone, daily nutrition support and micronutrients

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A meta-analysis of randomized controlled trials: Efficacy of selenium treatment for sepsis

by S Li, T Tang, P Guo, Q Zou, X Ao, L Hu, and L Tan

Published in Medicine, March 2019. doi: 10.1097/MD.0000000000014733


Researchers aimed to better understand the clinical outcomes of selenium therapy in patients with sepsis syndrome by conducting a meta-analysis of randomized controlled trials (RCT).


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High burden of co-morbidity and mortality among severely malnourished children admitted to outpatient therapeutic programme facilities in the conflict setting of Borno, Nigeria: a retrospective review

by Chamla D, Oladeji O, Maduanusi I, Mele S, Mshelia H, and Safi N

Published in Public Health Nutrition, 19 February 2019. doi: 10.1017/S1368980018003968



The study objective was to present evidence on the burden and outcomes of co-morbidities among severely malnourished (SAM) children admitted to outpatient therapeutic programme (OTP) facilities in the conflict setting of Borno, Nigeria.

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