Burden of Invasive Pneumococcal Disease

By Mary Slack, Andrew Vyse, Harish Madhava, Gillian Ellsbury, Carole Czudek, Ralf-Rene Reinert, Bradford Gessner. Published in Clinical Infectious Diseases. October 15, 2019.  


TO THE EDITOR—We read with interest the article by Kent et al [1]. The authors note that the burden of invasive pneumococcal disease (IPD) in UK infants aged <1 year is substantial and that the incidence of IPD in this age group increased over the study period (2013–2016). Although the majority of IPD cases (369/454, 71.4%) were due to non–13-valent pneumococcal conjugate vaccine (PCV13) serotypes, disease also was caused by PCV13 (vaccine type [VT]) serotypes (85/454, 16.4%), with a limited reduction in VT IPD from 36 cases in 2013 to 28 cases in 2016. Serotype 3 was the most common VT serotype identified…

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Monday, 17 February 2020