By Pui-Ying Iroh Tam, Patrick Musicha, Kondwani Kawaza, Jenifer Cornick, Brigitte Denis, Bridget Freyne, Dean Everett, Queen Dube, Neil French, Nicholas Feasey,Robert Heyderman
Clinical Infectious Diseases, To be Published July 2019
The adequacy of the World Health Organization’s Integrated Management of Childhood Illness (IMCI) antimicrobial guidelines for the treatment of suspected severe bacterial infections is dependent on a low prevalence of antimicrobial resistance (AMR). We describe trends in etiologies and susceptibility patterns of bloodstream infections (BSI) in hospitalized children in Malawi.
We determined the change in the population-based incidence of BSI in children admitted to Queen Elizabeth Central Hospital, Blantyre, Malawi (1998–2017). AMR profiles were assessed by the disc diffusion method, and trends over time were evaluated.